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Medchemexpress LLC Rosiglitazone-d3 | 1132641-22-5 | 97.2% | 360.45 | 1 MG
Supplier: Medchemexpress LLC HY17386S1MG
Rosiglitazone-d3 is the deuterium labeled Rosiglitazone. Rosiglitazone is a selective, orally active PPARγ agonist with EC50s of 30 nM, 100 nM, and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively. It binds to PPARγ with a Kd of approximately 40 nM and is also an activator of TRPC5 and an inhibitor of TRPM3. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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