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Medchemexpress LLC Rosuvastatin sodium | 147098-18-8 | 99.9% | 503.52 | 1 ML
Supplier: Medchemexpress LLC HY17504B10MM/1ML
Rosuvastatin Sodium is a potent and selective competitive inhibitor of HMG-CoA reductase (HMGCR) with an IC50 of 11 nM. It also potently blocks hERG current with an IC50 of 195 nM. This compound reduces the expression of mature hERG and its interaction with heat shock protein 70 (Hsp70), contributing to its biological activity. Rosuvastatin Sodium is effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. It is intended for research use only.
- Competitive HMG-CoA reductase (HMGCR) inhibitor
- Potently blocks hERG current
- Reduces expression of mature hERG protein
- Lowers LDL cholesterol and triglycerides
- Reduces C-reactive protein levels
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