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Apexbio Technology LLC RS 504393 300816-15-3 50mg
SDP

Supplier:  Apexbio Technology LLC A377950

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RS 504393 (CAS 300816-15-3) is a small molecule antagonist selective for the CCR2 chemokine receptor It demonstrates potent inhibition of human recombinant CCR2b with an IC50 of 98 nM while exhibiting markedly reduced activity against CCR1 (IC50 100 M) RS 504393 effectively suppresses MCP-1-induced chemotaxis (IC50 330 nM) and has been shown to attenuate kidney injury following ischemia-reperfusion This compound is commonly employed in biomedical research to investigate CCR2-mediated signaling pathways inflammatory cell recruitment and the role of chemokine receptors in renal and inflammatory pathologies

Catalog No. 50-000-96499


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