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Medchemexpress LLC Ru-ski 43 hydrochloride | 1782573-67-4 | 98.8% | 423.01 | 50 MG
Supplier: Medchemexpress LLC HY18366A50MG
RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. It also exhibits anti-cancer activity.
- Potent and selective Hhat inhibitor (IC50 = 850 nM).
- Reduces Gli-1 activation via Smoothened-independent non-canonical signaling.
- Decreases Akt and mTOR pathway activity.
- Possesses anti-cancer activity.
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