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Selleck Chemical LLC Ruxolitinib (INCB018424) 100mg 941678-49-5
Supplier: Selleck Chemical LLC S1378100MG
Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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