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Selleck Chemical LLC Ruxolitinib Phosphate S5243-1g

Supplier: Selleck Chemical LLC S52431G
Ruxolitinib Phosphate (INCB018424 INC424) is the phosphate salt form of Ruxolitinib Ruxolitinib is the first potent selective JAK1/2 inhibitor to enter the clinic with IC50 of 3 3 nM/2 8 nM in cell-free assays 130-fold selectivity for JAK1/2 versus JAK3 Ruxolitinib kills tumor cells through toxic mitophagy Ruxolitinib induces autophagy and enhances apoptosis
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