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Selleck Chemical LLC Ruxolitinib Phosphate 25mg 1092939-17-7 INCB018424, INC424
Supplier: Selleck Chemical LLC S524325MG
Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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