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Medchemexpress LLC S-14506 hydrochloride | 286369-38-8 | 99.9% | 443.94 | 10 MG
Supplier: Medchemexpress LLC HY11002450MG
S-14506 hydrochloride is a potent 5-HT1A agonist and a 5-HT2A/2C antagonist. It also exhibits dopamine antagonist properties by blocking dopamine D2 receptors, inhibiting the in vivo binding of [3H]raclopride in the striatum and olfactory bulbs. This compound has potential for research as an anxiolytic agent.
- Potent 5-HT1A agonist
- 5-HT2A/2C antagonist
- Exhibits dopamine antagonist properties by blocking dopamine D2 receptors
- Inhibits in vivo binding of [3H]raclopride
- Potential for anxiolytic agent research
- High affinity for G protein-uncoupled state of 5-HT receptor in HeLa cells
- Dose-dependently antagonizes apomorphine-induced stereotyped climbing and sniffing in mice
- Active in the forced swimming test in rats, inducing immobility
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