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Medchemexpress LLC (S)-2,2-dimethyl-1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one | 2049868-46-2 | 99.1% | 230.31 g/mol | C14H18N2O | 1 ML
SDP

Supplier:  Medchemexpress LLC HY103028A10MM 1ML

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GSK963 is a chiral, highly potent, and selective small-molecule inhibitor of RIP1 (RIPK1) kinase with an IC50 of 29 nM; it is used to block necroptosis in murine and human cells in vitro.

  • Potent RIP1 kinase inhibitor (IC50 29 nM).
  • Chiral small molecule with high selectivity for RIP1.
  • Provided as a 10 mM solution in DMSO, 1 mL, for in vitro use.
  • High purity (~99.1% by HPLC).
  • Molecular weight 230.31 g/mol; chemical formula C14H18N2O.
  • Suitable for cellular and biochemical studies of necroptosis and RIP1 signaling.

Catalog No. 50-002-46313


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