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Medchemexpress LLC (S,R,S)-AHPC-PEG4-NH2 hydrochloride | 2064292-52-8 | 98.2% | 700.29 g/mol | C32H50ClN5O8S | 50 MG

Supplier: Medchemexpress LLC HY10360450MG
(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase VHL ligand-linker conjugate used as a PROTAC building block. It combines an (S,R,S)-configured AHPC VHL ligand with a four-unit PEG linker terminating in a primary amine, providing a conjugation handle for assembling bifunctional degraders.
- VHL ligand core for recruiting the VHL E3 ligase.
- Four-unit PEG linker imparts flexibility and improves solubility.
- Terminal primary amine enables straightforward conjugation to warheads or linkers.
- High purity suitable for research synthesis (≈98.2%).
- Water solubility up to 50 mg/mL (ultrasonic may be required) for formulation convenience.
- Supplied as a hydrochloride salt to aid stability and handling.
- Intended for use as a PROTAC intermediate in targeted protein degradation research.
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