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Medchemexpress LLC (S,R,S)-AHPC-propargyl | 2098799-78-9 | 99.5% | 526.65 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12645650MG

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(S,R,S)-AHPC-propargyl is a VHL ligand used in "click reactions" for PROTACs. It functions as a click chemistry reagent containing an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. VHL protein, a substrate recognition subunit of Cullin RING E3 ubiquitin ligase complexes, is frequently recruited by PROTACs to induce ubiquitination and subsequent proteasomal degradation of target proteins.

  • VHL ligand for PROTACs.
  • Click chemistry reagent with an alkyne group.
  • Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc).
  • Recruits VHL protein for ubiquitination and degradation of target proteins.
  • Used in PROTAC synthesis.
  • Applicable in cancer targeted therapy.

Catalog No. 50-004-38083


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