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Medchemexpress LLC (S,R,S)-AHPC-propargyl | 2098799-78-9 | 99.5% | 526.65 | 50 MG

Supplier: Medchemexpress LLC HY12645650MG
(S,R,S)-AHPC-propargyl is a VHL ligand used in "click reactions" for PROTACs. It functions as a click chemistry reagent containing an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. VHL protein, a substrate recognition subunit of Cullin RING E3 ubiquitin ligase complexes, is frequently recruited by PROTACs to induce ubiquitination and subsequent proteasomal degradation of target proteins.
- VHL ligand for PROTACs.
- Click chemistry reagent with an alkyne group.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc).
- Recruits VHL protein for ubiquitination and degradation of target proteins.
- Used in PROTAC synthesis.
- Applicable in cancer targeted therapy.
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