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Medchemexpress LLC S1P1 agonist III | 1324003-64-6 | 99.6% | 1 ML
Supplier: Medchemexpress LLC HY1283510MM/1ML
S1P1 agonist III is an orally active hS1P1 agonist with an EC50 value of 18 nM. It exhibits limited activity against hS1P3 and can be utilized in research pertaining to multiple sclerosis.
- Orally active hS1P1 agonist with an EC50 of 18 nM.
- Shows limited activity against hS1P3.
- Used in research of multiple sclerosis.
- Induces potent internalization of hS1P1 receptors in U2OS cells with an EC50 of 0.018 μM.
- Exhibits moderate permeability across LLC-PK1 porcine proximal tubule cells.
- Highly stable in rat liver microsomes.
- Causes a statistically significant reduction of circulating blood lymphocytes in Lewis rats.
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