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Medchemexpress LLC S1R agonist 1 (Compound 6b) | 193354-70-0 | ≥98.0% | 295.42 | 5 MG
Supplier: Medchemexpress LLC HY1498035MG
S1R agonist 1 (Compound 6b) is a selective S1R agonist with Ki values of 0.93 nM for S1R and 72 nM for S2R. It demonstrates neuroprotection against ROS and NMDA-induced neurotoxicity, and significantly increases nerve growth factor (NGF) induced neurite outgrowth in PC12 cell lines.
- Selective S1R agonist
- Neuroprotective against ROS and NMDA-induced neurotoxicity
- Increases nerve growth factor (NGF) induced neurite outgrowth in PC12 cell lines
- Prevents cell damage induced by rotenone in SHSY5Y cells
- Exhibits no cytotoxicity against A549, LoVo, and Panc-1 cells (within 0-10 μM)
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