Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC SAG dihydrochloride | 2702366-44-5 | 98.2% | 25 MG
Supplier: Medchemexpress LLC 25MGHY12848C
SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). It activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo. It is for research use only.
- Molecular weight: 562.98
- Chemical formula: C28H30Cl3N3OS
- Appearance: solid
- Color: light yellow to light brown
- Potent Smoothened (Smo) receptor agonist
- Activates the Hedgehog signaling pathway
- Counteracts Cyclopamine inhibition of Smo
- Induces firefly luciferase expression in Shh-LIGHT2 cells
- Competes for BODIPY-cyclopamine binding to Smo-expressing Cos-1 cells
- Increases SMO mRNA and protein expression in MDAMB231 cells
- Increases MDAMB231 cell migration
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?