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Apexbio Technology LLC Salmeterol xinafoate 94749-08-3 50mg
Supplier: Apexbio Technology LLC A378950
Salmeterol xinafoate (CAS 94749-08-3) is a long-acting 2-adrenergic receptor agonist that induces smooth muscle relaxation leading to bronchodilation and vasodilation In vitro studies show that salmeterol reduces retinal M ller cell death by inhibiting IRS-1 (Ser307) phosphorylation implicating -adrenergic signaling in cell survival pathways In vivo experiments demonstrate that salmeterol suppresses pro-inflammatory cytokine production in allergen-stimulated murine models and attenuates inflammatory responses via modulation of dendritic cells Clinically salmeterol has been shown to enhance peak expiratory flow in asthma and is studied in combination therapies for persistent asthma supporting its utility in respiratory and immunological research
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