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Apexbio Technology LLC Sarafloxacin HCl 91296-87-6 1g
Supplier: Apexbio Technology LLC B18281000
Sarafloxacin hydrochloride (91296-87-6) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV It is designed to inhibit these essential enzymes thereby disrupting bacterial DNA replication Sarafloxacin hydrochloride exerts its biological activity primarily through stabilization of enzyme-DNA complexes leading to interference with bacterial DNA synthesis and cell death It demonstrates anti-microbial activity against various Gram-positive and Gram-negative bacterial strains with reported IC50 values against bacterial enzyme targets in the submicromolar range Based on these pharmacological properties sarafloxacin hydrochloride holds research potential in studies of bacterial resistance mechanisms susceptibility profiling and the pharmacodynamics of quinolone antibiotics
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