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Medchemexpress LLC Saralasin ([Sar1,Ala8] Angiotensin II) | 34273-10-4 | MFCD00167510 | 99.5% | 912.05 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP02055MG

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Saralasin, an octapeptide analog of angiotensin II, acts as a competitive angiotensin II receptor antagonist (Ki: 0.32 nM for 74% binding sites) and also exhibits partial agonist activity. It is used in research for renovascular hypertension and renin-dependent hypertension.

  • Functions as a competitive angiotensin II receptor antagonist
  • Exhibits partial agonist activity
  • Inhibits cell growth in 3T3 and SV3T3 cells
  • Restores I*to*, fast and I*K*, slow to control levels in myocytes
  • Ameliorates oxidative stress and tissue injury in cerulein-induced pancreatitis
  • Increases serum renin activity in normal, conscious rats
  • Inhibits binding of FITC-Ang II to rat liver membrane preparation
  • Reduces ovulation rate and prostaglandin E2 and 6-keto-prostaglandin F1α levels in vitro

Catalog No. 50-004-26281


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