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Enzo Life Sciences SB 225002 (5mg). CAS: 182498-32-4
SDP

Supplier:  Enzo Life Sciences ALX270478M005

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Potent and selective antagonist of CXCR2 chemokine receptor (IC50=22nM). >150-fold more selective over CXCR1 receptor. Inhibits IL-8- (IC50=8nM) and GROα-mediated (IC50=10nM) calcium mobilisation. Prevents IL-8-induced neutrophil migration. Inhibits HIV replication in lymphocytes and macrophages. Alternative name: N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea. Purity: ≥98% (HPLC). Appearance: Yellow solid. Solubility: Soluble in DMSO (40mg/ml), 100% ethanol or methanol (15mg/ml); slightly soluble in acetonitrile (2mg/ml). Long Term Storage: -20°C.

Catalog No. 50-200-8605


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