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Medchemexpress LLC SB-277011 hydrochloride | 215804-67-4 | 99.59% | 475.02 | 100 MG
Supplier: Medchemexpress LLC HY10847B50MG
SB-277011 hydrochloride is a potent, selective, orally bioavailable, and brain-penetrant dopamine D3 receptor (D3R) antagonist. It exhibits high selectivity over other dopamine receptors, making it suitable for targeted research. The compound has an excellent pharmacokinetic profile in rats, demonstrating good oral bioavailability and brain penetration.
- Potent and selective D3 receptor antagonist
- Orally bioavailable and brain-penetrant
- Displays high selectivity over other dopamine receptors
- Reverses quinelorane effects in nucleus accumbens
- Reduces intravenous cocaine self-administration
- Inhibits basal and cocaine-enhanced locomotion
- Suitable for research use only
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