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Medchemexpress LLC SB-747651A (dihydrochloride) | 1781882-72-1 | 99.14% | 415.32 | 25 MG
Supplier: Medchemexpress LLC 25MGHY110313
SB-747651A dihydrochloride is an ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1) with an IC₅₀ of 11 nM. It also inhibits PRK2, RSK1, p70S6K, and ROCK-II. This compound is used in inflammation research.
- ATP-competitive MSK1 inhibitor
- Inhibits PRK2, RSK1, p70S6K, and ROCK-II
- Suitable for inflammation research
- Modulates chemokine-induced neutrophil recruitment
- Affects neutrophil extravasation in acute inflammation models
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