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Cayman Chemical SchIsndrIn A 10mg
Supplier: Cayman Chemical 1984910 MG
A lignan with diverse biological activities; binds to adiponectin receptor 2 (IC50 = 3.2 µM); reduces LPS-induced production of NO, IL-6, and TNF-α and apoptosis in primary mouse microglial cells at 10, 20, and 50 µM; reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells at 20 µM; reverses Aβ42-induced short-term and spatial memory deficits, as well as decreases in cerebral SOD and GPX activities in a mouse model of Alzheimer's disease at 4, 12, and 36 mg/kg
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