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Apexbio Technology LLC Schizandrin B(Synonyms: Schisandrin B, Gomisin N, γ-Schisandrin, Schizandrol B, Wuweizisu-B), 10mg, CAS: 61281-37-6.
Supplier: Apexbio Technology LLC N165610
Schizandrin B (CAS 61281-37-6) is a dibenzocyclooctadiene lignan isolated from Schisandra fruit It exhibits antioxidant activity by scavenging hydroxyl and superoxide radicals inhibiting lipid peroxidation in vitro through NADPH/ascorbate and cysteine/iron systems In mouse models of doxorubicin-induced cardiotoxicity Schizandrin B reduces cardiac lipid peroxidation protein nitration metalloprotease activation cardiomyocyte apoptosis DNA damage and inflammation via suppression of MAPK-p38 phosphorylation and p53 activation These properties make Schizandrin B valuable for investigating oxidative stress-related cardiovascular injury
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