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Medchemexpress LLC Sec61-IN-1 | 2484865-42-9 | 99.7% | 430.53 | 100 MG
Supplier: Medchemexpress LLC HY139615100MG
Sec61-IN-1 is a potent sec61 inhibitor, which effectively targets glioma cells and enhances T cell cytotoxic effects. It has demonstrated efficacy in both in vitro and in vivo studies.
- Enhances T cell cytotoxicity in U87 glioma cells
- Exhibits lower IC50 for cytotoxicity in GBM12 and GBM38 PDX cell lines with SEC61G-EGFR dual amplification
- Detected in mouse brain tissue 45 minutes after intravenous injection
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