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Medchemexpress LLC Seco-DUBA | 1227961-59-2 | 98.1% | 526.97 | C29H23ClN4O4 | 25 MG
Supplier: Medchemexpress LLC HY132180A25MG
Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups that enable coupling to an antibody via a linker. It is intended as an ADC payload for synthesis and study of antibody-drug conjugates.
- A duocarmycin-based prodrug designed for ADC applications.
- Contains two hydroxyl groups suitable for antibody coupling via a linker.
- Used in the synthesis of antibody-drug conjugates for targeted delivery studies.
- Exhibits dose-dependent cytotoxicity comparable to DUBA.
- Demonstrates high in vitro potency against multiple cancer cell lines (reported IC50 values).
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