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Medchemexpress LLC Selegiline hydrochloride | 14611-52-0 | 99.96% | C13H18ClN | 100 MG
SDP

Supplier:  Medchemexpress LLC HY14199100MG

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Selegiline hydrochloride (Deprenyl) is a potent, selective, and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. It exhibits 450-fold selectivity for MAO-B over MAO-A (IC50=23 μM). This compound is used in research for Parkinson's disease, Alzheimer's disease, and major depressive disorder.

  • Potent, selective, irreversible MAO-B inhibitor.
  • IC50 of 51 nM for MAO-B.
  • 450-fold selectivity for MAO-B over MAO-A.
  • Research applications: Parkinson's, Alzheimer's, major depressive disorder.
  • Inhibits recombinant human MAO-B.
  • Increases efflux of NE, DA, and 5-HT from rat hypothalamus in vitro.
  • Reduces cocaine self-administration in mice.

Catalog No. 50-003-53450


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