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Apexbio Technology LLC Selpercatinib 2152628-33-4 25mg
Supplier: Apexbio Technology LLC A464725
Selpercatinib (CAS 2152628-33-4) is a potent selective inhibitor of rearranged during transfection (RET) tyrosine kinase receptors By preferentially targeting RET over other receptor tyrosine kinases selpercatinib disrupts aberrant RET signaling implicated in oncogenic transformation and tumor proliferation Unlike earlier multikinase inhibitors selpercatinib s enhanced specificity reduces off-target kinase inhibition thereby minimizing associated toxicities The compound has demonstrated clinical benefit in RET-driven cancer models and is used in research focused on targeted therapy development for malignancies characterized by RET alterations
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