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Medchemexpress LLC Seltorexant | 1293281-49-8 | 99.8% | 407.44 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10901210MG

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Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). It crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain.

  • Target: Orexin-2 Receptor (OX2R)
  • Activity: Orally active, high-affinity, and selective antagonist
  • Brain permeability: Crosses the blood-brain barrier and rapidly occupies OX2R binding sites in the rat brain
  • Purity: 99.83%
  • Form: Solid
  • Color: White to yellow
  • Research use: Used for research purposes
  • Sleep-promoting effects: Dose-dependently induces and prolongs sleep in male Sprague-Dawley rats, with effects maintained upon 7-day repeated dosing.

Catalog No. 50-003-46637


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