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Medchemexpress LLC Seralutinib | 1619931-27-9 | 99.94% | 469.53 | 100 MG
Supplier: Medchemexpress LLC HY10919010MM/1ML
Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. It also targets CSF1R and c-KIT with IC50s of 8 nM and 14 nM, respectively. This product is used in the study for pulmonary arterial hypertension.
- Inhaled PDGFRα and PDGFRβ inhibitor
- Targets CSF1R and c-KIT
- Used in the study for pulmonary arterial hypertension
- Significantly reduces right ventricular systolic pressure and mean pulmonary artery pressure
- Reduces pulmonary arteriole muscularization
- Restores BMPR2 protein expression in the lung lobes
- Well tolerated
- Appearance: Solid, white to light yellow
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