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Apexbio Technology LLC Sertaconazole nitrate 99592-39-9 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B18315.1
Sertaconazole nitrate (CAS 99592-39-9) is a small-molecule inhibitor targeting lanosterol 14 -demethylase It is designed to inhibit fungal ergosterol biosynthesis thereby disrupting fungal cell membrane synthesis and integrity Sertaconazole nitrate exerts its biological activity primarily through interference with lanosterol 14 -demethylase and direct interaction with fungal cell membranes In in vitro studies sertaconazole nitrate demonstrates inhibitory activity with IC50 values generally ranging between 0 1 2 g/mL against various pathogenic fungal organisms Based on these pharmacological properties sertaconazole nitrate holds research potential in antifungal susceptibility testing and experimental studies of dermatophytes and superficial mucocutaneous fungal infections
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