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Medchemexpress LLC Sesamol | 533-31-3 | 138.12 | 100 G
Supplier: Medchemexpress LLC HYN1417100G
Sesamol, a constituent of sesame oil, exhibits potent free radical scavenging, anti-oxidant, and anticancer activities, acting as a classical inhibitor of lipid peroxidation. It effectively induces apoptosis in human liver hepatocellular carcinoma (HepG2) cells by impairing mitochondrial function and suppressing autophagy. Sesamol also suppresses cell proliferation and triggers both intrinsic and extrinsic apoptosis pathways.
- Free radical scavenger
- Anti-oxidant and anticancer properties
- Inhibits lipid peroxidation
- Induces apoptosis in HepG2 cells
- Suppresses cell proliferation
- Triggers intrinsic and extrinsic apoptosis pathways
- Impairs mitochondrial function
- Inhibits mitophagy and autophagy
- Reduces anti-apoptotic protein Bcl-2
- Activates extrinsic apoptosis (Fas/FasL, tBid, caspase-8)
- Inhibits M-HeLa cell growth
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