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Medchemexpress LLC SHP389 5mg | 2235394-90-6 | 5 MG
Supplier: Medchemexpress LLC HY1144535MG
SHP389 is a small-molecule allosteric inhibitor of the SHP2 (PTPN11) phosphatase that inhibits SHP2 enzymatic activity and downstream p-ERK signaling. It is intended for biochemical and cellular research and supplied as a small solid quantity suitable for laboratory use.
- Allosteric inhibition of SHP2 with reported IC50 36 nM
- Inhibits p-ERK signaling in cellular assays
- Demonstrated antiproliferative activity in select cell lines (IC50 4.13 μM)
- Molecular formula C23H29ClN8O2; molecular weight 484.98 g·mol⁻¹
- Provided as a solid small-quantity package for research use
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