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Medchemexpress LLC Sildenafil (citrate) | 171599-83-0 | C28H38N6O11S | 10 G
SDP

Supplier:  Medchemexpress LLC HY15025A10G

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Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. This compound is intended for research use only.

  • Potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
  • Increases the phosphorylation of ERK1/ERK2.
  • Potentiates cell proliferation.
  • Enhances the upregulation of ERK1/ERK2 phosphorylation induced by serotonin.
  • Significantly increases intracavernosal pressure (ICP) and ICP/blood pressure (BP) ratio in dog models.
  • Decreases the number of TL+-cells.
  • Reduces the number of microglia/macrophages.
  • Decreases flap necrosis by increasing the secretion of growth factors.

Catalog No. 50-003-75917


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