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Medchemexpress LLC Silychristin | 33889-69-9 | 482.44 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYN06471MG

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Silychristin is an abundant flavonolignan found in the fruits of Silybum marianum, possessing antioxidant properties. It acts as a potent inhibitor of the thyroid hormone transporter MCT8, and strongly inhibits T3 uptake with an IC50 of 110 nM. It causes no cytotoxic effects for fibroblasts and diminishes UVA toxicity, reducing ROS generation in a dose-dependent manner.

  • Potent inhibitor of thyroid hormone transporter MCT8.
  • Strongly inhibits T3 uptake with an IC50 of 110 nM.
  • Possesses antioxidant properties.
  • No cytotoxic effects for fibroblasts.
  • Diminishes UVA toxicity.
  • Reduces ROS generation in a dose-dependent manner.
  • Reduces metalloproteinase-1 (MMP-1) level in cells.

Catalog No. 50-003-88845


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