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Medchemexpress LLC Simufilam hydrochloride | 2480226-07-9 | >99.9% | 295.81 | 100 MG
Supplier: Medchemexpress LLC HY139142B100MG
Simufilam hydrochloride is an orally active FLNA modulator. It restores NMDAR signaling and Arc expression, inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, and reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation. It can be used for research of Alzheimer's disease.
- Restores NMDAR signaling and Arc expression
- Inhibits overactive mTOR signaling by restoring the normal conformation of FLNA
- Improves insulin sensitivity
- Reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation
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