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Medchemexpress LLC Simvastatin-d6 | 1002347-71-8 | 99.6% | 424.60 | 1 ML
Supplier: Medchemexpress LLC HY110231500UG
Simvastatin-d6 is a deuterium-labeled form of Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase with a Kᵢ of 0.2 nM. The incorporation of stable heavy isotopes into drug molecules makes it useful as a tracer for quantitative analysis during drug development. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes for quantitation during drug development.
- Deuteration may impact pharmacokinetic and metabolic profiles of drugs.
- Functions as a competitive inhibitor of HMG-CoA reductase.
- Exhibits a high affinity with a Kᵢ of 0.2 nM for HMG-CoA reductase.
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