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Medchemexpress LLC Smart1 (PROTAC Smurf1 degrader) | 99.9% | 753.76 | C40H35N9O7 | 5mg
SDP

Supplier:  Medchemexpress LLC HYW9983455MG

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SMART1 is a highly specific and CRBN-dependent PROTAC that can effectively degrade Smurf1 SMART1 can block the PDK1-Akt signaling pathway in KRAS mutant colorectal cancer SMART1 can inhibit tumor growth in KRAS mutant colorectal cancer (CRC) xenograft models (Blue CRBN ligand Black linker Pink Smurf1 ligand (Smurf1-L)) [1] br/

Catalog No. 50-002-70366


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