Apexbio Technology LLC SNX-2112 908112-43-6 100mg

Supplier:  Apexbio Technology LLC A4068100

SNX-2112 (CAS 908112-43-6) is a potent synthetic inhibitor of heat shock protein 90 (Hsp90) exhibiting an IC50 of 30 nM against its target Hsp90 a molecular chaperone broadly expressed in cells assists in the folding and stabilization of various client proteins including kinases and transcription factors implicated in cancer such as Bcr-Abl EGFR and c-Met SNX-2112 disrupts Hsp90 function leading to the degradation of client proteins and subsequent inhibition of signaling pathways essential for tumor cell survival In cancer cell models SNX-2112 has demonstrated cell growth inhibition (e g A-375 IC50 1 25 M) and induces apoptosis and cell cycle arrest This compound is widely used in preclinical studies to investigate Hsp90-dependent oncogenic processes and potential therapeutic strategies

Catalog No. 50-000-96815