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Selleck Chemical LLC Sodium dichloroacetate (DCA) 100mg 2156-56-1 Dichloroacetic acid, bichloroacetic acid, BCA
Supplier: Selleck Chemical LLC S8615100MG
Sodium dichloroacetate (DCA, Dichloroacetic acid, bichloroacetic acid, BCA), a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 ?M for PDK2 and PDK4 respectively, has been shown to derepress Na+-K+-2Cl- cotransporter and a mitochondrial potassium-ion channel axis. Sodium dichloroacetate increases reactive oxygen species (ROS) generation, triggers apoptosis in cancer cells, and inhibits tumor growth. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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