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Selleck Chemical LLC Sorafenib 50mg 284461-73-0 BAY 43-9006

Supplier: Selleck Chemical LLC S739750MG

Sorafenib (BAY 43-9006) is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-?, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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