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Abcam Spiperone hydrochloride, 5-HT and D2-like receptor antagonist, 50MG
Supplier: Abcam AB12054950MG
MW 431.9 Da, Purity >98%. 5-HT and D2-like receptor antagonist. (IC50 values are 1.6 and 15 nM at 5-HT2 and 5-HT1C receptors, respectively. Ki values are 0.06 ( D2), 0.6 (D3), 0.08 (D4), ~ 350 (D1) and ~ 3500 nM (D5)). Potently enhances intracellular Ca2+ levels. Additionally activates Ca2+-activated Cl- channels (CaCC) to induce Cl- secretion.
The product is subject to the following: Abcam Restricted Use Statement
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