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Medchemexpress LLC SPOP-IN-6b dihydrochloride | 99.7% | 573.51 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY122615B10MG

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SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM. It is intended for research use only and not for sale to patients.

  • Potent SPOP inhibitor with an IC50 of 3.58 μM.
  • Suppresses SPOP activity, leading to an increase in suppression cancer substrate proteins PTEN and DUSP7 content in vitro (IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells).
  • Slows down tumor growth in nude mice by suppressing SPOP (40-80 mg/kg; intraperitoneal injection; daily; for 25 days).

Catalog No. 50-004-37201


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