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Apexbio Technology LLC SR 202 76541-72-5 10mg
Supplier: Apexbio Technology LLC B692910
SR 202 (CAS 76541-72-5) is a small-molecule antagonist targeting peroxisome proliferator-activated receptor gamma (PPAR ) It is designed to selectively suppress PPAR -mediated transcriptional activity thereby regulating adipogenesis and glucose homeostasis pathways SR 202 exerts its biological activity primarily by inhibiting thiazolidinedione-induced recruitment of coactivators to PPAR and attenuating ligand-dependent adipocyte differentiation In vitro studies demonstrate that SR 202 reduces PPAR -driven adipogenic processes and inhibits thiazolidinedione-induced transcriptional activation with an IC50 of 140 M Based on these pharmacological properties SR 202 holds research potential in the study of obesity insulin resistance and type 2 diabetes
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