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Selleck Chemical LLC SR-4835 S8894-25MG

Supplier: Selleck Chemical LLC S889425MG
SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4 9 nM for CDK13 SR-4835 disables triple-negative breast cancer (TNBC) cells SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors
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