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Medchemexpress LLC SsK36 TFA | 99.3% | 1771.04 (free base) | 5 MG
Supplier: Medchemexpress LLC HYP10463A5MG
ssK36 TFA is a supersubstrate peptide of the histone methyltransferase (SET) domain protein 2 (SETD2). It is designed for the SETD2 protein, a specific PKMT, responsible in human cells for adding methyl groups to the 36th lysine residue of histone H3 (H3K36) to form H3K36me3. This peptide can be methylated by SETD2 at a rate more than 100 times faster than the natural substrate H3K36 and can be used to study the catalytic mechanism of PKMTs, especially substrate specificity and catalytic efficiency.
- Purity of 99.34%
- Molecular weight of 1771.04 (free base)
- Formula: C79H127N29O18.xC2HF3O2
- Appearance: Solid
- Color: White to off-white
- Sequence: Ala-Pro-Arg-Phe-Gly-Gly-Val-Lys-Arg-Pro-Asn-Arg-Tyr-Arg-Pro
- Sequence shortening: APRFGGVKRPNRYRP
- Solubility (in vitro): 1 mg/mL in H2O (requires ultrasonic)
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