Medchemexpress LLC STAT3-IN-3 | 2361304-26-7 | 98.4% | 100 MG

Supplier:  Medchemexpress LLC HY128588100MG

STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3). It exhibits anti-proliferative activity by inducing apoptosis in breast cancer cells and is considered a promising mitochondria-targeting STAT3 inhibitor for cancer research. This compound inhibits STAT3 tyrosine and serine phosphorylation and its DNA-binding activity. In vivo studies have shown potent antitumor activity against implanted 4T1 breast tumors.

• Potent and selective STAT3 inhibitor
• Induces apoptosis in breast cancer cells
• Mitochondria-targeting for cancer research
• Inhibits STAT3 phosphorylation and DNA-binding
• Down-regulates STAT3 target genes
• Increases ROS production
• Reduces mitochondrial membrane potential
• Induces caspase cleavage
• Exhibits anti-proliferative activity
• Potent antitumor activity in vivo

Catalog No. 50-003-41884