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Reprocell STEMOLECULE PURMORPHAMINE 5MG
Supplier: Reprocell 040009
Purmorphamine is a small molecule that promotes the differentiation of human and murine mesenchymal progenitor cells into osteoblasts. The mechanism of action study of Purmorphamine indicates that it is an agonist of Smoothened, a 7-transmembrane receptor of the hedgehog signaling pathway. Purmorphamine can also be used to replace sonic hedgehog for the generation of motor neurons from human embryonic stem cells. Size: 5mg. Molecular weight: 520.6. Purity: Greater than 96% by HPLC analysis. For a 10 mM concentrated stock solution of Purmorphamine, reconstitute the compound by adding 960.4 ul of DMSO to the entire contents of the vial. If precipitate is observed, warm the solution to 37C for 2 to 5 minutes. For use in cell culture, warm the medium just prior to adding the reconstituted compound. Once the compound is added, mix and filter-sterilize the medium using a 0.2 uM low-protein binding filter. Purmorphamine is soluble in DMSO at 50 mM. 483367-10-8
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