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Medchemexpress LLC STING agonist-23 | 2361570-16-1 | C33H35N13O4 | 5 MG
Supplier: Medchemexpress LLC HY1529565MG
STING agonist-23 (CF502) is a non-nucleotide small-molecule STING agonist. It activates STING and increases the phosphorylation of STING, TBK1, and IRF3. It promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells, and shows activity against SARS-CoV series strains.
- Activates STING, increasing the phosphorylation of STING, TBK1, and IRF3.
- Elevates levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells.
- Demonstrates activity against SARS-CoV series strains.
- Induces a strong antibody immune response when combined with SARS-CoV-2 RBD-Fc protein in a mouse model (adjuvant activity).
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