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Medchemexpress LLC STING agonist-26 | 2868261-48-5 | C40H49N15O5 | 25 MG
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Supplier:  Medchemexpress LLC 25MGHY152959

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STING agonist-26 (CF508) is a non-nucleotide small-molecule STING agonist. It activates STING and increases phosphorylation of STING, TBK1, and IRF3.

  • Promotes levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells.
  • Exhibits activity against SARS-CoV series strains.
  • Increases phosphorylated STING, TBK1, and IRF3 levels after 3 hours in THP-1 cells.
  • Increases IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 levels after 5 hours in THP-1 cells.
  • Induces strong antibody immune response when combined with SARS-CoV-2 RBD-Fc protein in a mouse model.

Catalog No. 50-003-74727


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