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Sigma Aldrich Fine Chemicals Biosciences Streptavidin Maleimide fro2MG
Supplier: Sigma Aldrich Fine Chemicals Biosciences S94152MG
Streptavidin is a protein produced by the bacterium Streptomyces avidinii. It has four binding sites for biotin as does avidin. Both have been used extensively as probes in immunochemical systems conjugated to antibodies enzymes or fluorochromes. However avidin is highly basic (pI ~ 10.5) compared to streptavidin (pI ~ 5-6). Avidin has a slightly higher binding capacity for biotin than streptavidin does but it has glycosylated side chains which give higher backgrounds in blotting techniques than does streptavidin which is not a glycoprotein. Streptavidin is more resistant than avidin to dissociation into subunits by guanidinium chloride.
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