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Medchemexpress LLC Streptozotocin | 18883-66-4 | 99.15% | 265.22 | 1 G
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Supplier:  Medchemexpress LLC HY137531G

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Streptozotocin (STZ) is an antibiotic widely used in experimental animal models of induced diabetes. It enters B cells via the glucose transporter (GLUT2) and causes DNA alkylation, leading to the apoptosis of β cells.

  • Used in experimental animal models of induced diabetes
  • Suitable for constructing models of type 1 and type 2 diabetes
  • Highly water-soluble
  • Distributes widely throughout the body, including crossing the blood-brain barrier and placenta
  • Induces cytotoxicity, oxidative stress, and mitochondrial dysfunction in HepG2 cells

Catalog No. 50-003-51827


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